The 100,000 Genomes Project

The 100,000 Genomes Project will sequence 100,000 genomes from around 70,000 people. Participants are NHS patients with a rare disease, plus their families, and patients with cancer.

The aim is to create a new genomic medicine service for the NHS – transforming the way people are cared for. Patients may be offered a diagnosis where there wasn’t one before. In time, there is the potential of new and more effective treatments.

The project will also enable new medical research. Combining genomic sequence data with medical records is a ground-breaking resource. Researchers will study how best to use genomics in healthcare and how best to interpret the data to help patients. The causes, diagnosis and treatment of disease will also be investigated. This is currently the largest national sequencing project of its kind in the world.

Who is involved?

The project is being run nationally by Genomics England. Genomics England is working together with NHS England, Health Education England and Public Health England to deliver the 100,000 Genomes Project. NHS Genomic Medicine Centres (GMCs), such as us (Yorkshire and Humber NHS Genomic Medicine Centre), have been set up across the country to recruit patients, take the samples and provide medical information to the project.

So, what is genomics?

Genomics is an area within genetics that concerns the sequencing and analysis of an organism’s genome. The genome is the entire DNA content that is present within one cell of an organism. Find out more about genomics on our dedicated page here

What will the Yorkshire and Humber NHS Genomic Medicine Centre do?

The Yorkshire and Humber is very proud to have been established as one of 13 NHS Genomics Medicine Centres across England.

Our aim in the Yorkshire and Humber Genomic Centre is to collect samples from 4,700 participants with rare diseases plus their families, and patients with certain types of cancer, including breast, colorectal, lung, prostate, ovarian and sarcoma by December 2017.

You can find out a bit more about the Yorkshire and Humber NHS Genomic Medicine Centre here